As
biostimulators continue to gain traction in aesthetic medicine, their
integration with other aesthetic procedures is emerging as a leading trend.
Combining therapies can yield enhanced results, offering synergistic effects
that support natural regeneration, longer-lasting outcomes, and more holistic
facial rejuvenation.
Why Combine Treatments?
Biostimulators
like PLLA, CaHA, or RH collagen work by activating fibroblasts and enhancing
the production of collagen and elastin. However, their effects are gradual.
When paired with more immediate interventions, such as hyaluronic acid fillers,
neuromodulators, energy-based devices (e.g., RF, microneedling), or chemical
peels, patients can benefit from both instant results and long-term skin
improvements.
Common Combination Protocols
- Biostimulators + HA Fillers: This is one of the most
popular combinations. While HA provides volume restoration and contouring
with instant gratification, biostimulators work in the background to
improve skin density and elasticity over time.
- Biostimulators + Toxins
(Botulinum Toxin): Administering a neuromodulator to reduce dynamic lines can allow
biostimulators to work more effectively by minimizing repeated muscle
movement in treated areas.
- Biostimulators +
Microneedling/RF: Energy-based treatments trigger micro-injuries and further
stimulate fibroblasts, complementing the regenerative actions of collagen
stimulators. This duo often leads to improved skin texture and firmness.
- Biostimulators + Peels or PRP: In protocols aiming to
resurface or rejuvenate the skin, adding biostimulation can elevate the
longevity and quality of outcomes.
Timing and Sequencing: A Critical Factor
Combination
treatments require expert timing. Administering procedures too close together
can cause irritation or interfere with product performance. Typically,
practitioners:
- Begin with neuromodulators,
allowing 10–14 days for effect.
- Inject HA fillers for immediate
contouring.
- Apply biostimulators in a
layered approach, often in separate sessions.
- Introduce energy-based or
resurfacing treatments once the skin has stabilized.
Best Practices and
Considerations
- Patient Assessment is Key: Not all patients benefit
equally from combined treatments. A thorough consultation determines
appropriate pairings based on age, skin condition, and aesthetic goals.
- Start Conservatively: Especially when integrating
biostimulators with devices, a conservative protocol minimizes the risk of
inflammation or overcorrection.
- Educate Patients: Set realistic expectations.
Biostimulators take time to show results, but they can significantly
enhance the effects of faster-acting therapies.
Clinical Outcomes and Patient Satisfaction
Studies and
anecdotal reports highlight increased patient satisfaction when biostimulators
are combined with complementary treatments. Results tend to be more natural,
balanced, and durable. Over time, the skin becomes thicker, firmer, and more
radiant, with fewer touch-up needs.