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Table of Contents

Introduction

SunekosPerforma is the latest innovation in skin biostimulation, combining low molecular weight hyaluronic acid (LMW‑HA) with a patented blend of six amino acids (the HY6AA formula). Designed to restore the extracellular matrix (ECM), it aims to regenerate collagen types IV and VII as well as elastin and fibronectin—offering a foundational approach to skin rejuvenation rather than just superficial plumping.

Product Portfolio & Comparison

  • Pre-mixed formula: Each vial contains ~35mg LMW-HA (50250kDa) and ~128mg amino acids (glycine, proline, lysine, leucine, valine, alanine), in a precise stoichiometric balance tuned for regenerating dermal matrix.
  • Stronger than Sunekos200: Offers ~28% more amino acids and ~17% more HA, making it approximately 30% more potent—and more suitable for demanding skin types and broader coverage areas.

Mechanism of Action & Innovation

  1. Targeted ECM regeneration: The HY6AA formula encourages fibroblast differentiation into active ECM producers, supporting synthesis of collagen (types I, IV, VII) and elastin in physiologic ratios.
  2. Reduced HA degradation: The specially balanced amino acids slow hyaluronidase activity—extending the residency of HA in the dermis and enhancing stimulation longevity.
  3. Hydration and anti‑inflammatory effects: LMW‑HA improves skin hydration, elasticity, and offers mild anti-inflammatory support.

Clinical Applications & Protocol

  • Indications: Face (including under-eyes), neck, décolleté, hands, and other thin or aging-prone areas.
  • Protocol: Typically 3–4 sessions spaced every 7–14 days. One vial per session covers full face; first visible improvements at ~10 days, with final effects lasting up to 6–12 months.
  • Injection techniques: Microbolus, interstitial fluid flow (IFT), or cannula in mid-to-deep dermis; massage afterward encourages lymphatic flow and distribution.

Benefits & Results

  • Natural‑looking improvements: Enhanced skin firmness, elasticity, hydration, and subtle volume restoration.
  • Broad ECM regeneration: Supports true structural rejuvenation—not just superficial moisture.
  • Minimal downtime: Generally mild swelling or bruising; suitable even for under-eye applications.
  • Longer lasting than conventional boosters: Due to reduced enzymatic breakdown and ECM activation.

Safety & Considerations

  • Non–cross-linked, low irritation profile: Unlikely to provoke inflammation or allergic response.
  • Technique-sensitive: Requires precise injection depths and post-care massage to minimize blebs or irregularity.

Why Choose Sunekos Performa

  • Balanced regenerative action: Collagen and elastin production at physiologic ratios restore skin structure from within.
  • Hydration plus ECM rebuilding: A dual approach differentiates it from purely hydrating skin boosters.
  • Versatility: Applicable in delicate regions and can complement other therapies like lasers or microneedling.
  • Well‑tolerated: A low-irritant option suitable even for sensitive under-eye areas.

Conclusion

Sunekos Performa represents a next-gen biostimulator designed for comprehensive ECM restoration. Its proprietary amino-acid‑plus‑Hyaluronic Acid formula promotes collagen and elastin synthesis in naturally balanced proportions, yielding improved skin density, elasticity, and overall texture with minimal downtime. While results are more subtle than volumizing fillers, the long-term structural benefits—coupled with its safe profile—make it a valuable option for patients seeking foundational skin renewal.

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e-BIOSTIMULATORS Team