About aesPlla®
aesPlla® is Oreon Life Science’s flagship injectable biostimulatory filler, based on Poly-L-Lactic Acid technology. Developed for aesthetic physicians seeking gradual, natural collagen remodeling, aesPlla® offers a long-lasting regenerative effect with a strong safety profile. Its reputation is built on consistent, progressive volumizing outcomes and its role as a strategic alternative to high-profile PLLA fillers like Sculptra® and Rejuplla®. Designed with meticulous particle size control and CE approval, aesPlla® is a trusted option for premium regenerative injectable protocols worldwide.

aesPlla® (365 mg PLLA Filler)
aesPlla® is a biocompatible, biodegradable Poly-L-Lactic Acid (PLLA) injectable powder presented in a 365 mg vial (for 5 ml dilution). It acts as a potent collagen stimulator, designed to restore facial volume, improve skin texture, and visibly rejuvenate the skin through controlled biostimulation. aesPlla® gradually induces fibroblast activity, triggering neocollagenesis, with effects designed to last up to 2–3 years after treatment.
Key Features
• Pure PLLA microparticles for safe, biocompatible, and effective collagen induction.
• Visible, natural-looking results gradually developing over 4–6 weeks, with progressive skin firming and volume restoration.
• Extended clinical longevity, offering results maintained for 2–3 years post-treatment.
• CE-certified product, manufactured under GMP-compliant conditions, ensuring regulatory safety and product consistency.
• Versatile treatment indications: suitable for full-face rejuvenation, volume loss correction, and collagen stimulation in areas such as cheeks, jawline, temples, and neck.
• Recognized globally, aesPlla® is available in 70+ markets and featured at international congresses including IMCAS and AMWC.
About Oreon Life Science
Oreon Life Science, established in 2000 in Seoul, South Korea, is a globally recognized manufacturer in the field of aesthetic medicine. Specializing in dermal fillers, regenerative biostimulators, mesotherapy solutions, and PDO lifting threads, Oreon is present in over 70 countries. Known for their advanced biotechnology, safety certifications, and clinical-grade innovation, they have positioned aesPlla® as a competitive, CE-certified injectable PLLA collagen stimulator within the regenerative aesthetics market.