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About Radiesse

Radiesse® is a renowned dermal filler developed by Merz Aesthetics, widely recognized for its innovative dual-action formula that offers both immediate volumization and long-term collagen stimulation. Since its FDA approval, Radiesse has become a preferred choice among aesthetic professionals looking to deliver natural, durable facial rejuvenation results.

What is Radiesse?

Radiesse is a calcium hydroxylapatite (CaHA) based injectable filler suspended in a smooth gel carrier. Unlike traditional fillers that provide volume by physically occupying space, Radiesse combines immediate filling effects with a unique ability to stimulate the body’s own collagen production.

Calcium hydroxylapatite is a naturally occurring mineral in human bones, making Radiesse highly biocompatible and safe for use in facial aesthetics.

Mechanism of Action

Radiesse works through a twofold mechanism:

  • Immediate Volume Restoration: The gel carrier provides instant lift and correction to wrinkles, folds, and areas of volume loss.
  • Collagen Biostimulation: As the gel is gradually absorbed, the CaHA microspheres trigger fibroblast activation, promoting new collagen synthesis. This process restores skin’s structural integrity and elasticity over time.

This biostimulatory effect can last up to 12-18 months, providing patients with sustained, natural-looking improvements.

Clinical Applications

Radiesse is FDA-approved for:

  • Correction of moderate to severe facial wrinkles and folds such as nasolabial folds.
  • Restoration of lost volume in the hands to reduce the appearance of veins and tendons.
  • Off-label uses include contouring of the cheeks, jawline, chin, and temples.

Its versatility makes Radiesse a valuable tool for full-face rejuvenation protocols.

Safety and Tolerability

Radiesse has an excellent safety profile supported by extensive clinical studies and widespread use. The calcium hydroxylapatite microspheres are biocompatible and biodegradable, metabolized naturally by the body.

Common side effects include temporary swelling, redness, bruising, or tenderness at the injection sites, which typically resolve within a few days.

Why Choose Radiesse?

  • Provides immediate and long-lasting results by combining volume and collagen stimulation.
  • Uses naturally derived CaHA microspheres for excellent biocompatibility.
  • Approved for facial and hand rejuvenation, offering versatility.
  • Stimulates collagen production, enhancing skin texture and elasticity over time.
  • Results last up to 18 months, outperforming many traditional fillers in durability.

Conclusion

Radiesse by Merz Aesthetics offers a unique approach to facial rejuvenation by blending instant volumization with progressive collagen biostimulation. Its dual-action formula makes it an outstanding choice for patients seeking natural, long-lasting results with minimal downtime.

For aesthetic practitioners, Radiesse provides a scientifically supported, reliable solution for restoring youthful contours and improving skin quality, making it a cornerstone injectable in regenerative aesthetic medicine.

e-BIOSTIMULATORS Team