Neauvia,
founded in 2012 and now distributed in over 80 countries, is at the forefront
of aesthetic innovation. Their line of precision hyaluronic acid (HA) fillers
is cross‑linked with polyethylene glycol (PEG) via patented Smart Crosslinking
Technology (SXT), yielding highly biocompatible and flexible gels that
integrate naturally with tissue and support regenerative outcomes.
Product Portfolio
Neauvia’s
diverse filler variants are tailored to various indications:
- STIMULATE: PEG‑HA enriched with calcium
hydroxylapatite (CaHA), combining volumization and biostimulation in one
gel.
- INTENSE, INTENSE RHEOLOGY, INTENSE
ROSE, INTENSE FLUX: PEG‑HA fillers with different rheologies
for facial contouring, wrinkle correction, and volumization.
- HYDRO DELUXE: A non‑crosslinked hydrogel
enriched with CaHA, ideal for hydration‑focused restoration.
Key Features &
Innovation
- PEG-Based Cross‑Linking (Smart
Crosslinking Technology)
By using PEGDE instead of traditional BDDE, Neauvia achieves superior gel plasticity, cohesivity, and viscoelasticity, resulting in natural movement, minimal swelling, and strong tissue integration. - Biomechanically Intelligent Gel
The filler’s matrix adapts to facial dynamics holding shape where needed while flexing with expressionsand remains stable under thermal stress, allowing safe combinations with lasers, RF, or ultrasound protocols. - Amino Acid Enrichment
Glycine and L‑proline are included for collagen synthesis support, reduced swelling, and enhanced integration, contributing to regulated collagen stimulation and comfort post‑injection. - Biostimulation via STIMULATE
STIMULATE uniquely fuses PEG‑HA with CaHA microspheres (~10 µm), creating dual-action volumizing and fibroblast-stimulating effects. This synergy stimulates neocollagenesis, improves firmness, and is clinically validated in a 24‑week observational study.
Clinical Applications
- Contouring & Volume
Restoration:
For cheeks, jawline, chin, nasolabial folds, and acne scars using INTENSE
variants or STIMULATE.
- Hydration & Skin Quality: HYDRO DELUXE enhances
hydration with smart viscosity and biostimulation via CaHA.
- Combination Protocols: Neauvia’s Smart Combination
Therapy blends fillers with energy‑based treatments (N‑LIFT, N‑BOOST),
amplifying regenerative outcomes.
- Areas Treated: Full-face, including delicate
zones like under eyes, temples, and hands, depending on product viscosity
and technique.
Benefits & Results
- Natural Look & Feel: PEG‑HA gels mimic natural
tissue mechanics, avoiding stiffness and overcorrection.
- Extended Duration: Products like HYDRO DELUXE
can last up to two years due to thermal stability and slow degradation.
- Minimal Swelling & High
Tolerance: Low
inflammatory response and minimal side effects observed in clinical and in
vitro studies.
- Award-Winning Innovation: STIMULATE earned “Best
Injectable Dermal Filler” at AMWC 2024 for its hybrid PEG‑HA + CaHA
design.
Safety & Regulatory
Oversight
- No BDDE Usage: PEG avoids concerns tied to
traditional crosslinkers. High biosafety and non-cytotoxicity are
demonstrated through in vitro and in vivo assessments.
- Thermo-Stable &
Biodegradable:
Maintains integrity under temps from –20°C to +75°C, permitting safe
multimodal protocols.
- Regulatory Compliance: All fillers are Class III
medical devices under EU MDR, manufactured by MatexLab (Italy).
Why Choose Neauvia?
- Smart rheology: gels that flex, adapt, and
feel naturally integrated with facial movements.
- Biocompatible formulation: PEG‑HA crosslinker avoids
BDDE-related risks.
- Tailored performance: A full portfolio from
volumizing to hydrating fillers, for specific indications.
- Evidence-backed: STIMULATE studied in
post-market trials; visible skin firmness and volumizing improvements at
six months.
- Holistic protocols: Engineered for use in
synergistic treatment plans combining energy devices and filler
strategies.
Conclusion
Neauvia
redefines filler technology through Smart PEG‑HA crosslinking paired with
strategic amino‑acid enrichment and optional CaHA, offering personalized,
biomechanically intelligent solutions. Whether restoring lost volume or
boosting skin quality, Neauvia’s precision formulations provide aesthetic
professionals with tools to deliver natural, long-lasting, and safe
rejuvenation.
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