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Optimizing Aesthetic Results: Pairing Biostimulators with Skincare Regimens

Pairing Biostimulators with Skincare Regimens

In the evolving field of aesthetic medicine, combining injectable biostimulators with targeted skincare regimens has emerged as a promising strategy to enhance skin rejuvenation outcomes. This integrated approach aims to address both the structural and surface-level aspects of aging, leading to more comprehensive and sustained aesthetic improvements.

Clinical Insights: A Comparative Study

A recent randomized, double-blinded, split-face clinical trial (NCT05963204) conducted by Galderma R&D explored the synergistic effects of pairing a biostimulator with a skincare regimen for midface rejuvenation. The study involved 21 participants with moderate-to-severe cheek wrinkles and mild-to-severe photodamage. Subjects were randomized to receive either Sculptra® in combination with Alastin Restorative Skin Complex or CeraVe Daily Moisturizing Lotion, with treatments administered at baseline, 6 weeks, 12 weeks, and 18 weeks. The primary outcome was assessed using Line-Field Optical Coherence Tomography to evaluate skin structural changes.

Mechanisms of Action

  • Biostimulators: Agents like poly-L-lactic acid (PLLA) stimulate collagen production, leading to improved skin density and elasticity over time.
  • Skincare Regimens: Products such as Alastin Restorative Skin Complex are designed to enhance skin health and complement the effects of injectable treatments by promoting skin barrier repair and reducing inflammation.

The combination of these modalities targets different layers and mechanisms of skin aging, potentially leading to more comprehensive rejuvenation.

Clinical Implications

Integrating biostimulators with skincare regimens may offer several benefits:

  • Enhanced Results: Combining treatments may lead to more significant improvements in skin texture and volume.
  • Sustained Outcomes: Skincare products can support the longevity of injectable treatments by maintaining skin health.
  • Patient Satisfaction: A holistic approach may improve overall patient satisfaction by addressing both immediate and long-term aesthetic concerns.

However, individual responses can vary, and personalized treatment plans should be developed to optimize outcomes.

Conclusion

The integration of biostimulators with tailored skincare regimens represents a promising advancement in aesthetic medicine, aiming to provide more comprehensive and lasting skin rejuvenation results. Further research and clinical experience will continue to refine these combination therapies, ensuring optimal outcomes for patients seeking to enhance their skin's appearance and health.

References


A Study to Evaluate the Effects for Midface Improvement When Pairing a Biostimulator with a Skincare Regimen


e-BIOSTIMULATORS Team