
Introduction
Radiesse
(and Radiesse +) is a calcium hydroxylapatite (CaHA)‑based dermal filler designed for
patients seeking correction of moderate to severe facial wrinkles and volume
loss—especially in the nasolabial folds,
jawline, and hands. It stands out by stimulating your body’s natural collagen
and elastin production, offering both an immediate volumizing effect and
long-term regenerative benefits.
Product Portfolio
Overview
- Radiesse: A CaHA microsphere gel for
facial correction and hand rejuvenation.
- Radiesse +: Enhanced jawline contouring, includes
lidocaine.
- Diluted/Hyperdiluted Radiesse: Tailored for skin tightening
on areas like neck, décolleté, and hands—without adding bulk.
Key Features &
Innovation
- Dual
Mechanism
- Immediate volume correction via the gel carrier.
- Sustained biostimulation: CaHA particles act as a
scaffold, inducing fibroblast activation—boosting collagen for up to a
year and elastin for ~9 months post-injection.
- Versatility
& Dilution Options
- Undiluted for volume;
hyperdiluted to focus on skin texture and firmness.
- Clinical series across 50+ patients showed up to 81.6% average skin improvement, with hyperdiluted protocols achieving up to 95% improvements in younger demographic groups.
- Longevity
& Satisfaction
- Results can last up to 18
months, often averaging 12 months in areas like nasolabial folds.
- High patient satisfaction:
after 4 months, 98% of patients were happy, with 93%
willing to repeat treatment and 94% able to recommend it.
Clinical Applications
& Results
- Facial Wrinkles & Volume
Loss: Smoothes
nasolabial and marionette lines, redefines jawline, restores cheek and
chin structures.
- Hand Rejuvenation: Corrects age-related volume
depletion in the dorsal hands.
- Skin Rejuvenation (Face, Neck,
Décolleté, Hands): Hyperdiluted injections significantly improved skin firmness,
brightness, elasticity, and vascularity across all age groups, with
minimal side effects.
Notable Study:
- 50 patients treated with
various dilution protocols (1:2 to 1:6)
- Over 80% across age brackets reported marked improvements; the youngest group (30–40 yrs) saw a 95% improvement in skin thickness and wrinkle reduction.
Why Choose Radiesse
- Natural look & feel: Immediate correction
transitions to natural collagen remodeling.
- Biocompatible & safe: CaHA microspheres mimic
bone/mineral physiology; no need for allergy testing.
- Highly customizable: Offers undiluted and diluted
versions, adapting to volume versus quality targets.
- Low downtime: Minor swelling/bruising; most
patients resume normal life quickly.
- High patient satisfaction: Most patients report
increased attractiveness, confidence, and repeat usage.
Scientific Support & Safety
Radiesse’s
effectiveness in stimulating neocollagenesis and neoelastinogenesis has been
validated through multiple studies, noting increases in collagen, elastin,
vascularization, proteoglycans, and fibroblasts. Safety profiles are favorable,
with typical side effects including bruising, swelling, and nodules—rare and
generally transient. Serious adverse events are very rare but include vascular
occlusion risks seen with dermal fillers.
Conclusion: Radiesse’s Market Position
Radiesse is
more than a volumizing filler—it’s a biostimulator that bridges
aesthetic results and regenerative science. Unique in its dual-action CaHA
platform, it’s suitable for volume restoration and skin rejuvenation alike.
With strong scientific backing, flexible formulations, and enduring patient
satisfaction, Radiesse is a trusted leader in regenerative facial rejuvenation.